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Detection of c-kit gene mutations in Exon 11 of Leukemias
Figure 1: SSCP-PAGE analysis of exon 11 (257 bp) shows electrophoresis mobility shift on native page. Lane 1 is the control, and lanes 2-5 are patients (no shift in patient 04, and a shift in patients 09, 11, and 20)
Detection of c-kit gene mutations in Exon 11 of Leukemias
Figure 2: Amino acid sequences of exon 11 of the c-kit gene. The sequence starts at codon 550 and ends at 591. The wild-type sequence is shown above. Point mutations are shown in
A novel 110-bp insertion in a patient with homocysteinuria
Figure 1. Agarose Gel Electrophoretic Analysis of the 110-bp Heterozygous Insertion at Exon 8 in the CBS Gene. Band 1 is the DNA Marker (ØX174 HaeIII, Fermentas), and Bands 2-6 are DNA Samples for the Control. Band 7 is The Patient’s PCR
A novel 110-bp insertion in a patient with homocysteinuria
Figure 2. Starting Point of the 110-bp Insertion at Exon 8 in the CBS Gene
A novel 110-bp insertion in a patient with homocysteinuria
Figure 3. CBS Gene 833 T>C Transition at Exon 8
Cloning of chimerical translocations as positive control for molecular genetic diagnosis of leukemia
Figure 1. Ethidium bromide stained agarose gel showing PCR from cloned fusion fragments. a) M-BCR-ABL, b)m- BCR-ABL, c) MLL-AF4, d)E2A-PB:1, e) PML-PARA variants, and f) t(12,21)
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